quebec has been one of the worst hit of canada's prove ins. the premier says only about 10% of quebec's population is unvaccinated, those people make up 50% of patients in intensive care. critics say such a penalty could face legal challenges. >> the worry is that it does set a precedent that this is the kind of thing that's permissible and so, you know, the same logic that applies to this measure would apply to, you know, taxing people because of certain other choices they make. >> reporter: after almost a year of pleading with people to get vaccinated, many european governments are losing patience with the holdouts. french president emmanuel macron says he wants to piss off the unvaccinated, but a growing number much places say it might be more effective to make them pay up instead. cnn, london. >>> french fashion designer manfred mugler tied at age 73. he was known for his provocative and exaggerated designs. he launched his first clothing label in 1973 before starting his self-named label. more recently he was known for styling iconic look

or as quebec puts it, the unvaccinated have a way to contribute to overwhelmed hospitals. we'll explain. >>> plus, the new poll has boris johnson going from bad to worse. the latest fallout from his party gate scandal just ahead. unlike ordinary memory supplements, neuriva plus fuels six key indicators of brain performance. more brain performance? yes, please! neuriva. think bigger. do you struggle to fall asleep and stay asleep? qunol sleep formula combines 5 key nutrients that can help you fall asleep faster, stay asleep longer, and wake up refreshed. the brand i trust is qunol. when they're sick, they get comfortable anywhere and spread germs everywhere. wherever they rest protection nothing kills more viruses, including the covid-19 virus, on more surfaces than lysol disinfectant spray. lysol. what it takes to protect. >>> welcome back to "cnn newsroom." i'm isa soares. if you're just joining us, let me bring you up to date with our top stories this hour. >>> nato diplomats are meeting in brussels this hour with russian officials to discuss tensions over ukraine. their

quebec, canada is providing evidence vaccine mandates do work. one day after the province announced it would impose fines on the unvaccinated, the health minister said there's been a spike in first-time appointments for vaccinations. the amount is unclear, but it would not apply to those with medical exemptions. 90% have at least one dose of a covid vaccine, but the government says the unvaccinated remain a huge burden on the province's health system. >>> meanwhile, the world health organization has a warning. do not take the omicron variant lightly. the w.h.o. chief says there were more than 50 million new covid cases worldwide last week. that is the most really in a single week, and that number was slightly underestimated. he added this huge spike in infections is being driven by the omicron variant. meantime, spain has reported its highest-ever covid-19 infection rate where the country's health minister said despite the rise in omicron cases, it is less stress on the health care system. germany said it should make covid-19 vaccines mandatory s